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High field MRI evaluation of different plaque property in Peyronie’s Disease

Zhang, Y1; Guan, J1; Xia, K1; Zhou, M1; Yang, Q1; Deng, C1

1: 1st affliated hospital of Sun Yat-sen University, China

Objectives: To analyze the MRI findings of Peyronie’s disease and investigate the diagnostic value for plaque property by using 3.0 Tesla MR.

Methods: 16 patients with clinically diagnosed Peyronie’s disease underwent 3.0T MR examination using a small surface coil were included. MR Imaging protocol included routine sequences(T1WI, T2WI and enhanced T1WI) and susceptibility weighted imaging (SWI) was performed. Each patient received 2-4 times of penile ultrasound examinationspreviously, and MRI results were compared with ultrasound.

Results: A total of 27 plaques in penile were found in all 16 patients, 4 cases with inflammatory (8 plaques), 4 with fibrotic (8 plaques)as well as 8 with calcified (11 plaques) were found respectively. All those 11 calcified plaques showed hypo-intense signal on SWI. Plaques with calcification can be stably detected by ultrasound (all 22 times of ultrasound examination for those 8 cases with calcified plaques were sensitively detected,22/22). The patients with inflammatory or fibrotic plaques could not be sensitively and accurately detected by ultrasound(8 plaques were found for 3 times out of 25 on ultrasound, all of which were fibrotic plaques). The combination of routine sequences and SWI scanning was necessary for the detection of calcified plaques, and the detection rates for inflammatory (0/7) and fibrotic (6/8) plaques by ultrasound were obviously lower than MRI (P<0.05).

Conclusions: High field MRI can detect plaques with different property through multi-parametric MRI, and help make early diagnosis.


Work supported by industry: no.

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