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A preliminary study of etiological factors in patients with calculi-associated seminal vesiculitis, based on calculus analysis in 6 patients

Wang, G1; Liu, G1; Wu, K1; Yin, W1; Wu, W1

1: Department of Urological Center, The Ningbo No1 Hospital, Zhejiang University, China

Objective: To conduct a preliminary analysis of etiological factors in patients with seminal vesicle calculi by performing composition analysis on calculus samples.

Methods: A retrospective analysis was performed on 6 patients with recurrent hematospermia who were diagnosed with seminal vesicle calculi using non-contrast pelvic computed tomography (CT). The patients were aged 28 to 69 years, and experienced persistent or recurring hematospermia for periods ranging from 3 months to 6 years. In particular, 5 patients had a history of acute urethritis. All patients underwent seminal vesiculoscopy. The procedure confirmed the presence of seminal vesiculitis associated with calculi, and calculus samples were removed using a spiral dislodger. A second-generation infrared calculus composition analyzer was used to determine the composition of the calculi. Patient follow-up was conducted 2 weeks to 3 months postoperatively, and reexamination with non-contrast pelvic CT was performed to determine the presence of recurrent reproductive tract calculi.

Results: CT indicated that at 3 months postoperatively, 3 patients had recurrence of seminal vesicle calculi. Of these, 2 had recurrent hematospermia, and recurrence was observed 1 month postoperatively in all cases. Among the 6 cases studied, the calculi in 5 cases were composed of struvite (magnesium ammonium phosphate hexahydrate), and the calculus of the remaining case was a mixture of calcium oxalate dihydrate, calcium oxalate monohydrate, and carbonate apatite.

Conclusion: Seminal vesicle calculi are most commonly composed of struvite, while other calculi are mainly composed of calcium oxalate dihydrate. The study results suggest that possible etiological factors in seminal vesiculitis associated with calculi are infection and reflux, with infection being the most common factor. It is believed that the determination of etiological factors for seminal vesiculitis and the use of individualized treatments will provide greater benefit for patients.


Work supported by industry: no.

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