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Female sexual dysfunction among Greek women with multiple sclerosis: correlations with organic and psychological factors

Tzitzika, M1; Konstantinidis, C1; Thomas, C1; Nikolia, A1; Kratiras, Z2; Samarinas, M2; Bantis, A1; Skriapas, K2

1: National Rehabilitation Center, Urology & Neuro-Urology Unit, Athens, Greece; 2: General Hospital "Koutlibanio", Urology department, Larisa, Greece

Objectives: Multiple Sclerosis (MS) is a degenerative, neurological disease which influences the patients’ QoL. Women with MS very often experience Female Sexual Dysfunction (FSD). The aim of our study is to determine and evaluate the prevalence of FSD in Greek women with MS and correlate it with organic and psychological factors.

Materials and Methods: 267 consecutive women with MS, aged over 18, who were admitted in our outpatient clinics from 02/2016 to 03/2017 were included in the study. Demographic data included age, marital status, menopause status, the number of children. Additionally, disease related data such as duration of the disease, Expanded Disability Status Scale (EDSS) and medication of MS was obtained. All participants completed the Greek validated version of the Depression, Anxiety, Stress Scale 21 (DASS-21) [15-17] questionnaire along with the Greek validated version of Female Sexual Function Inventory (FSFI). Statistical analysis was used to calculate the prevalence of FSD and its correlation with organic (age, EDSS, duration of the disease, menopause status) and psychological factors (Depression, Anxiety, Stress).

Results: FSD was diagnosed in 64.5% of our sample. The correlation analysis between clinical variables and FSFI subscales scores showed that age had a significant negative correlation with all subscales of the FSFI. Additionally, there was no significant correlation in any FSFI subscale with duration of the disease. Correlation of EDSS and FSFI scores found to be statistically significant with a negative correlation in all Subscales apart from the Satisfaction subscale. Regarding the correlation analysis between DASS domains and FSFI subscales, there were significant correlations in Desire and Arousal dysfunction with Depression, Anxiety and Stress and in Lubrication domain with Anxiety and Stress.

Conclusion: FSD is common among Greek female patients, it is influenced by the age, the severity of the disease and the co-existence of depression anxiety and stress.

Disclosure:

Work supported by industry: no.

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