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Quality of life and sexuality before and 6 months after surgery in breast cancer - a study within the itop trial, a prospective trial evaluating cosmetic and oncologic outcome of immediate techniques of oncoplastic surgery in breast cancer

Maghörndl, L1; Schneider, J2; Erlinger, P2; Dörfler, D3; Fitzal, F3

1: Hospital Mödling, Austria; 2: Medical University of Vienna, Austria; 3: Vienna General Hospital, Austria

Objective: Breast cancer is the most common type of cancer among women. However, by reaching 86%, the 5-year survival rate is very high. The radical mastectomy had been the procedure of choice for every operable carcinoma for a long time, but by now up to 73% of affected women receives a breast conserving therapy. The cosmetic outcome hereby can strongly affect the quality of life, which is why oncoplastic surgery has gained greater importance. The objective of this study was to compare patients’ quality of life who received a breast conserving therapy to those who additionally received an oncoplastic procedure.

Methods: Two different surgical procedures were evaluated in regards to patients’ quality of life and sexuality: The regular breast conserving therapy (BCT) and the breast conserving therapy with an immediate technique of oncoplastic surgery (BCT+iTOP). For evaluation, the BREAST-Q was used, which provides the quality of life domains psychosocial, physical and sexual well-being. Patients were interviewed the day before surgery for the first time and, as a follow up, 6 months after surgery. This study took place within the iTOP trial, which stands for immediate techniques of oncoplastic surgery. It's a prospective and non-randomised trial and was opened on the surgical department of the general hospital of Vienna in 2011.

Results: 55 patients were included in the BCT group and 31 in the BCT+iTOP group. Patients showed better psychosocial well-being within both groups 6 months after surgery than before surgery (p < 0,01). There was no significant difference over time in the domains physical and sexual well-being. The techniques BCT and BCT+iTOP were comparable regarding all three measured domains of quality of life six months after surgery.

Conclusion: None of the two procedures, BET or BET+iTOP, showed a clear advantage in regards to the quality of life and sexuality for the women. However, it seems to be very important to make individualized decisions when planning the surgical therapy. Thereby, the option of an oncoplastic procedure should always be mentioned and become a substantial component when considering possible options.


Work supported by industry: no.

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