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Metabolic syndrome is an independent risk factor for acquired premature ejaculation

Jeh, SU1; Yoon, S1; Do, J1; Seo, DH2; Lee, SW1; Choi, SM1; Lee, C2; Kam, SC2; Hwa, JS1; Chung, KH2; Hyun, JS1

1: Gyeongsang National University Hospital, Korea, South; 2: Gyeongsang National University Changwon Hospital

Objectives: We investigated the role of metabolic syndrome (MetS) as an independent risk factor for acquired premature ejaculation (PE) after considering the various risk factors of PE.

Materials and methods: From January 2012 to January 2017, records of 1,029 men were analyzed. We performed logistic regression analysis to identify independent risk factors for acquired PE, including the covariate of age, marital status, International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) score, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score, serum testosterone levels, and all components of MetS. Acquired PE was defined as self-reported intravaginal ejaculation latency time (IELT) < 3 minute, and MetS was diagnosed using the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria.

Results: Of 1,029 men, 74 (7.2%) had acquired PE and 111 (10.8%) had MetS. Multivariate analysis showed that the IIEF overall satisfaction score (OR 0.67, P < 0.001), NIH-CPSI pain score (OR 1.07, P = 0.035), NIH-CPSI voiding score (OR 1.17, P = 0.032), and presence of MetS (OR 2.20, P = 0.022) were significantly correlated with the prevalence of acquired PE. In addition, the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD) scores and ejaculation anxiety scores progressively decreased as the number of components of MetS increased.

Conclusions: MetS may be an independent predisposing factor for the development of acquired PE. Effective prevention and treatment of MetS could also be important for the prevention and treatment of acquired PE.


Work supported by industry: no.

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