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The Comparison of an acellular matrix graft (Xenoguardtm) with an autologous venous graft in the surgical treatment of Peyronie’s Disease

Kayigil, O1; Ozcan, MF2; Cakici, OU2

1: Yildirim Beyazit University Faculty of Medicine, The Urology Clinics of Ataturk Education and Research Hospital, Ankara, Turkey ; 2: Ankara Ataturk Education and Research Hospital, Department of Urology, Ankara, Turkey

Objectives: The aim of this study was to investigate the preliminary results of an acellular matrix graft (XenoguardTM) as a closure material for the tunica albuginea after plaque incision and compare the results with those obtained from patients treated by an autologous venous graft.

Materials and Methods: A XenoguardTM graft (Group 1) and an autologous saphenous vein graft (Group 2) were used in 27 and 26 patients, respectively for Peyronie’s correction. The patients’ age, body mass index (BMI), operation time, duration of follow up, preoperative and postoperative IIEF-5 scores, plaque size, and loss of sensation were evaluated in both groups.

Results: There were no differences between the two groups in terms of age, BMI, follow up period, and preoperative and postoperative IIEF-5 scores. The postoperative IIEF-5 scores were higher than the preoperative IIEF-5 scores in both groups. The operation time was significantly longer in Group 2 than in Group 1. The duration of sensation loss was shorter in Group 1 compared to Group 2. Penile shortening was similar in both groups.

Conclusions: XenoguardTM has a similar success rate, shorter operation time and shorter duration of sensation loss compared to autologous venous graft.


Work supported by industry: no.

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